WEHI Library – Screening identifies new compounds for HAT

Title Identification of compounds against Trypanosoma brucei brucei BS427 by high-throughput screening of whole parasites (87,926 compounds)
Partners
Eskitis Institute; The Walter and Eliza Hall Institute of Medical Research; University of Melbourne; Swiss Tropical and Public Health Institute
Target disease
Human African Trypanosomiasis (sleeping sickness)
Time frame November 2008 – December 2009

MMV Malaria Box

DNDi Screening of the MMV Open Access Malaria Box for HAT, VL, and Chagas disease

Title Screening of the MMV Open Access Malaria Box in the search for new drugs against Human African Trypanosomiasis (HAT), visceral leishmaniasis and Chagas disease.
Partners Medicines for Malaria Venture (MMV); University of Antwerp (LMPH)
Target disease Human African Trypanosomiasis (HAT); visceral leishmaniasis; Chagas disease
Time frame February 2012 – April 2012

SCYNEXIS Inc. as part of the DNDi HAT Lead Optimization Consortium

Title Screening and optimization of specific chemical series against human African Trypanosomiasis (HAT)
Partners
SCYNEXIS Inc. as part of the DNDi HAT Lead Optimization Consortium
Target disease
Human African Trypanosomiasis (HAT), also known as sleeping sickness
Time frame August 2006 – August 2010