DNDi Strategy for Visceral Leishmaniasis

Improved treatment options for VL patients in some areas have already been delivered. DNDi’s short-term approach has been to develop new treatments by combining existing drugs and/or shortening treatment duration in order to increase tolerability, reduce burden on health systems, and offer greater affordability, whilst also preventing or delaying emergence of resistance, and the geographical extension of existing drugs…

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DNDi Strategy for Cutaneous Leishmaniasis

For CL, DNDi’s objective is to develop short, safe, efficacious, affordable, and field-adapted treatments, at least for lesions caused by L. tropica and L. braziliensis. As a medium-term strategy, DNDi is developing a topical treatment based on amphotericin B. In addition, we aim to improve treatment strategies using currently available treatment modalities and will be evaluating a…

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