What is Malaria?


198 million new cases [1]
584,000 deaths [1]
3.3 billion people at risk
55,111,095 DALYs
Malaria is the leading parasitic cause of morbidity and mortality worldwide, especially in developing countries where it has serious economic and social costs. Malaria is thought to slow annual economic growth by 1.3% in endemic areas with high prevalence. The economic cost of malaria in Africa alone is estimated at US$12 billion every year.


Malaria is present in over 100 countries and threatens half of the world’s population. In sub-Saharan Africa, where it is the single largest cause of death for children under five, malaria kills nearly one child every minute – approximately 1,300 children every day.


Transmitted from person to person by the bite of anopheline mosquitoes, malaria is caused by the Plasmodium parasite. Four species are involved: P. falciparum, P. malariae, P. vivax, P. ovale.& P. falciparum is the main cause of severe clinical malaria and death.


Malaria begins as a flu-like illness 8 to 30 days after infection. Symptoms include fever (with or without other signs or symptoms such as headache, muscular aches and weakness, vomiting, diarrhea). Typical cycles of fever, shaking chills, and drenching sweats may then develop. Death may be due to brain damage (cerebral malaria), or damage to vital organs.


Patient treatment needs
Patients in malaria-endemic countries need inexpensive, efficacious, and field-adapted drugs.


malaria_factsheet_cover_mini   DNDi Malaria Fact-sheet




[1] In 2013, according to the World Malaria Report 2014
[2] Global Burden of Disease 2012: http://www.who.int/entity/healthinfo/global_burden_disease/GHE_DALY_WHOReg6_2000_2012.xls