Uniting to Combat Neglected Tropical Diseases
View the archived webcast of the 30 January event.Featuring Bill Gates, Margaret Chan, DFID and USAID representatives, 9 pharmaceutical company CEOs, senior government officials, Bernard Pécoul and others.
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SCYNEXIS Inc. as part of the DNDi HAT Lead Optimization Consortium
Screening and optimization of specific chemical series against human African Trypanosomiasis (HAT): 4926 compounds
DNDi Lead Optimization Consortium (Epichem, Murdoch University, CDCO):
Optimization of fenarimol series for the treatment of Chagas disease: 751 compounds
PORTFOLIO
Current portfolio:Working in partnership with industry and academia, DNDi has built the largest ever R&D portfolio for the kinetoplastid diseases.
New disease areas:
DNDi has decided to take on two new mini-portfolios: paediatric HIV and helminth infections.
PUBLICATIONS
DNDi model: status and challenges"Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges" by Shing Chang and Jean-Robert Ioset Future Medicinal Chemistry. 2011 September
Paediatric HIV: A neglected disease?
"Pediatric HIV - A Neglected Disease?" by Lallemant M et al. The New England Journal of Medicine. 2011 August
Novel drug candidate for HAT
"SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis" by Jacobs R.T et al. PLoS NTD. 2011 June
R&D for helminth infections
"Potential Drug Development Candidates for Human Soil-Transmitted Helminthiases" by Olliaro P et al. PLoS NTD. 2011 June
Past
Jan 30, 2012
Uniting to Combat Neglected Tropical Diseases
London, UK
On the occasion of the high-level event, DNDi welcomed the commitments from various partners and emphasized that filling major gaps in R&D are urgently needed to develop new treatments for neglected patients.
Dec 4-8, 2011
60th ASTMH
Philadelphia, USA
DNDi team participated with presentations on Leishmaniasis East Africa Platform and on Chagas disease, as well as with several posters and a DNDi booth.
Dec 2, 2011
DNDi Partners' Meeting 2011
Rio de Janeiro, Brazil
DNDi brought together over 260 health researchers, policy makers, and experts to stimulate greater regional research partnership to fight the most neglected diseases.
Jan 30, 2012
Uniting to Combat Neglected Tropical Diseases
London, UK
On the occasion of the high-level event, DNDi welcomed the commitments from various partners and emphasized that filling major gaps in R&D are urgently needed to develop new treatments for neglected patients.
Dec 4-8, 2011
60th ASTMH
Philadelphia, USA
DNDi team participated with presentations on Leishmaniasis East Africa Platform and on Chagas disease, as well as with several posters and a DNDi booth.
Dec 2, 2011
DNDi Partners' Meeting 2011
Rio de Janeiro, Brazil
DNDi brought together over 260 health researchers, policy makers, and experts to stimulate greater regional research partnership to fight the most neglected diseases.
DNDI NEWS
DNDi in the Media
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