Future use and needs of fixed-dose
combinations in malaria-endemic countries |
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According to WHO, forty nine countries have already adopted Artesunate combination Therapy as their national first-line treatment.
12 African Countries and Indonesia have already adopted AS/AQ. Other countries are expected to switch to fixed-dose combinations once these become available, and many other countries may choose to adopt them.
Assessing the future need for ACT, the World Health Organization has forecast that in 2005, 90 to 150 million treatments will be needed (based on total morbidity estimates). Africa, the worst-hit continent, makes up 60-70% of this global need. To meet the high demand several industrial partners will need to be involved in the manufacture of both combinations at low cost.
All malaria-endemic countries will benefit from the availability of a wider range of safe, effective and easy to use fixed-dose combinations.
Thirteen countries have already adopted the combination of artesunate/amodiaquine as their national first line treatment and five have adopted artesunate/mefloquine.
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