ASMQ to treat Malaria

Fixed dose combination of Artesunate + Mefloquine
First new malaria treatment made in Latin America,
for Latin America, South East Asia and Africa!
  • Launched in 2008
  • Included in the Essential Medicines List (EML) and Essential Medicines List for children (EMLc) of the WHO in 2013
  • Developed by an innovative collaboration between DNDi, Brazil and South-East Asia within the FACT Project Consortium
  • Produced by Farmanguinhos/Fiocruz (Brazilian public pharmaceutical company)
  • The 2-in-1 combination ensures that both drugs are taken together in correct proportions
  • Simple and Adapted Regimen for Children and Adults. As Easy as 1-2-3!
  • Adapted Packaging: 3 years shelf life: the longest shelf life of any FDC for malaria.
  • High compliance and low risk of resistance
  • WHO Prequalification in September 2012
  • Registered in Brazil in 2008, in India in 2011, in Malaysia and Myanmar in 2012; in Tanzania in 2013; in Vietnam, Niger and Burkina Faso in 2014; and in Thailand and Cambodia in 2015
  • Successful South-South technology transfer from Farmanguinhos to Cipla Ltd, India
  • Admission of Farmanguinhos/Fiocruz to the PAHO Strategic Fund in April 2013 will allow procurement by South American national control programs
  • Soon available in other countries in Latin America, Southeast Asia and Africa
  • Handed over to the MMV Access and Product Management team in May 2015 to help maximize patient access – read statement

Download ASMQ brochure, September 2012 [1.9MB]
Download ASMQ scientific document, September 2012 [1.3MB]
Download ASMQ press pack, April 2008 [1.1MB] Read more about ASMQ project

 

 ASMQ News
Implementation progress

Handed over to MMV Access team

ASMQ: registered in Thailand and Cambodia!

Farmanguinhos/Fiocruz admitted to PAHO Strategic Fund

830’000 treatments distributed

Recent Scientific Publications

Journal of Antimicrobial Chemotherapy, June 2014

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina FasoMalaria Journal, May 2014
Population pharmacokinetics of mefloquine, administered as a fixed-dose combination of artesunate-mefloquine in Indian patients for the treatment of acute uncomplicated Plasmodium falciparum malaria

Malaria Journal, December 2013
Safety, efficacy and population pharmacokinetics of fixed-dose combination of artesunate-mefloquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in India