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Paediatric Benznidazole

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An improved treatment option
 
  • Age-adapted, easy-to-use, affordable, and non-patented tablet, for the treatment of Chagas
  • disease in infants and young children under 2 years of age (20 kg body weight).
  • Contributes to improved dosing accuracy, safety, and adherence to treatment
  • Granted registration by Brazil’s National Health Surveillance Agency (ANVISA), with further endemic countries targeted for obtaining registration.


Main advantages of the Paediatric dosage form of Benznidazole
  • A single tablet allows coverage of a wide age range, up to 2 years old or body weight 20 kg
  • Child-adapted dose of 12.5 mg per tablet
  • Easily dispersible tablet to facilitate oral administration
  • No need for tablet fractionation (except for low-birth weight babies <2.5 kg: half a tablet)
  • Simple and reliable administration that does not require complex preparation and can therefore be administered at home, even during the long duration of treatment (twice daily for 60 days)

A collaborative partnership
Result of a three-year collaborative partnership, starting in 2008, between DNDi and the Pernambuco State Pharmaceutical Laboratory (Laboratório Farmacêutico do Estado de Pernambuco; LAFEPE) of Brazil. LAFEPE is the second largest public laboratory in Brazil and the only producer of benznidazole in the world.

Download Paediatric Benznidazole dossier (12/2011) [PDF]


   


 


Pediatric Benznidazole News
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Granted registration in Brazil in late 2011!

Isabela Ribeiro, Poster
Population Pharmacokinetics of Benznidazole in Children......


 


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