Drug development for neglected diseases: a deficient market and a public-health policy failure

by Trouiller, P. et al. The Lancet, June 2002, 359:2188–94.

Summary: There is a lack of effective, safe, and affordable pharmaceuticals to control infectious diseases that cause high mortality and morbidity among poor people in the developing world. This paper analyses outcomes of pharmaceutical research and development over the past 25 years, and reviews current public and private initiatives aimed at correcting the imbalance in research and development that leaves diseases that occur predominantly in the developing world largely unaddressed.

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