Advances in leishmaniasis

by Murray HW, Berman JD, Davies CR, Saravia NG. The Lancet, Oct 29-Nov 4 2005, 366(9496):1561-1577.

Summary: Diagnosis relies on visualising parasites in tissue or serology; culture and detection of parasite DNA are useful in the laboratory. Despite tangible advances in diagnosis, treatment, and basic scientific research, leishmaniasis is embedded in poverty and neglected. Current obstacles to realistic prevention and proper management include inadequate vector (sandfly) control, no vaccine, and insufficient access to or impetus for developing affordable new drugs.

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