SCYNEXIS and DNDi Extend Collaboration to Identify Drug Candidates to Treat Sleeping Sickness

[ December 11, 2008 ]
“SCYNEXIS believes that this collaborative project approach with DNDi can play an important role in improving the discovery and development of new therapies for neglected diseases,” said SCYNEXIS President & CEO Yves Ribeill. “We are pleased with the progress this alliance has achieved to date and look forward to continuing to apply our expertise in drug discovery and development to identify new drug candidates to treat sleeping sickness.”

Positive Results for Improved Treatment Against Sleeping Sickness

[ New Orleans, USA; Paris, France; Geneva, Switzerland – December 9, 2008]
Pivotal Phase III clinical trial results conclusively show that Nifurtimox-Eflornithine Combination Therapy (NECT) is well tolerated and effective against the advanced stage of T. b. gambiense sleeping sickness, a fatal disease that threatens 60 million people in sub-Saharan Africa.
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Coarsucam™ (artesunate/amodiaquine) first fixed-dose antimalarial combination to receive WHO Prequalification

Significant Step towards Expanded Global Access to Malaria Treatment
[Paris, France, and Geneva, Switzerland – October 16, 2008]
Sanofi-aventis and the non-profit Drugs for Neglected Diseases initiative (DNDi) welcome the approval, by the World Health Organization (WHO) Prequalification of Medicines Program, of Coarsucam™ / Artesunate Amodiaquine Winthrop® (“ASAQ”), the first fixed-dose combination of the two antimalarial compounds, artesunate (AS) and amodiaquine (AQ).

DNDi calls on G8 leaders to increase their commitment to neglected tropical diseases

[ Geneva – June 30, 2008 ]
Immediately following the Drugs for Neglected Diseases initiative (DNDi) Stakeholders’ Meeting on June 26, 2008, and in advance of the upcoming 2008 G8 Summit in Japan, DNDi released a statement endorsed by World Health Organization (WHO) urging the G8 governments to support both control programs and research & development (R&D) initiatives for neglected tropical diseases.

DNDi Receives Goodwin Award for Its Social Entrepeneurial Approach for the Most Neglected

[ Siena, Italy; Geneva, Switzerland – May 8, 2008 ]
The University of Siena today awarded the Drugs for Neglected Diseases initiative (DNDi) with a Goodwin Award for its innovative needs-driven approach in making 2 new antimalarials available as public goods, and in engaging public and private partners worldwide, especially in neglected disease-endemic countries, to ensure that the best science is made available for those neglected patients.

A Worldwide Public Partnership Makes Available a New, Once-a-Day Fixed-Dose Combination against Malaria

[ Rio de Janeiro – April 17, 2008 ]
An innovative partnership between the Brazilian public pharmaceutical company, Farmanguinhos/Fiocruz, and the non-profit drug development organization, Drugs for Neglected Diseases initiative (DNDi), announced today that ASMQ, the new fixed-dose combination of artesunate (AS) and mefloquine (MQ), is now registered and available in Brazil.
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