In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

by Longo M, Zanoncelli S, Messina M, Scandale I, Mackenzie C, Geary T, Marsh K, Lindley D, Mazué G. Reproductive Toxicology 2014, doi:10.1016/j.reprotox.2014.06.009.

Summary: Flubendazole, in a new formulation with high systemic bioavailability, has been proposed as a macrofilaricide against filarial diseases. The embryotoxic activity of a new oral flubendazole formulation was investigated. It did not interfere with rat embryofetal development.

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