Antileishmanial and antitrypanosomal drug identification

by Croft SL, Chatelain E, Barrett MP.  Emerging Topics in Life Sciences 2017, 1(6): 613-620, doi 10.1042/ETLS20170103.

Summary: Treatments for human African trypanosomiasis (HAT), leishmaniasis and Chagas disease (CD) still rely on drugs developed several decades ago, but there has been significant recent progress in the identification, development and use of novel drugs and formulations. The authors provide an updated review of the drug development pipeline and new tools, and identify several key research gaps.

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