[Closing date: October 31, 2017]
The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients’ needs-driven, non-profit drug research and development (R&D) organization that is developing new treatments for Neglected Diseases (www.dndi.org – www.gardp.org)
The Global Antibiotic Research & Development Partnership (GARDP) is a not-for-profit research and development organization that addresses global public health needs by developing and delivering new or improved antibiotic treatments, while endeavoring to ensure sustainable access. Initiated and incubated through close collaboration between WHO and Drugs for Neglected Diseases initiative (DNDi), GARDP is part of the implementation of the Global Action Plan on Antimicrobial Resistance that calls for new public-private partnerships for encouraging research and development of new antimicrobial agents and diagnostics.
GARDP’s mission is to work in partnership with the public and private sectors, to develop and deliver new treatments for bacterial infections where drug resistance is present or emerging, or for which inadequate treatment exists.
GARDP is currently hosted and facilitated by DNDi, which provides the scientific environment, necessary personnel, and infrastructure to ensure an effective start-up phase.
Purpose of the position
The antimicrobial memory recovery project:
One of the key projects that GARDP is currently preparing for launch by the end of the year is the Antibiotic Memory Recovery Programme. Antibiotic Memory Recovery Programme aims to identify, compile, and share know-how, information and assets from existing resources – human, electronic, and material – within an open access platform in order to stimulate and enhance the antibiotic drug discovery and development ecosystem at large by:
- Identifying and maintaining contact with researchers and drug developers active, or that were active in the field of antibiotic R&D and that hold specific information on forgotten, withdrawn, or abandoned antibiotics that could be relevant to today’s needs. This will include Memory recovery and scoping of potential old, abandoned or stalled R&D programmes, including those identified by GARDP SAC advisors, consultants and staff;
- With the Business Development team, identifying, evaluating and scoping for specific collaborations with relevant entities in order to accelerate R&D of the most relevant Antibiotic Memory Recovery Programme compounds according to GARDP’s mandate;
- Managing the identification and bringing together of relevant molecule collections (including structures, materials, compounds, and reagents) to be shared in an ‘antibiotic memory box’ to research groups, along data, key individuals involved, and any new information generated by others in an open source manner;
- In collaboration with CARB-X, producing educational material (webinars, guidelines, digests, etc.) centered around antibiotic drug research and development and putting them online through the REVIVE hub (see below).
The REVIVE hub:
An additional goal of the Antibiotic Memory Recovery Programme is to give the larger community of antibiotics researchers and product developers access to the knowledge of the expert group through an internet portal through which “users” and “experts” can be communicating and exchanging questions and experiences.
The hub will also contain a searchable database of the information gathered through the Antibiotic Memory Recovery Programme, which will be openly shared. Lastly, the portal will also host educational resources produced by the Antibiotic Memory Recovery Programme activities, as well as useful links to additional databases, tools and references.
Specific job responsibilities
Tasks and responsibilities:
- Drive the Antibiotic Memory Recovery Programme project and its workstreams, and propose additional workstreams to strengthen the program;
- Research, build and maintain a solid network of active and retired antibiotic drug discovery and development experts worldwide;
- Organize and manage the experts’ group so as to maximize the benefits for the anti-infective community and GARDP’s activities;
- Research and build a historical list of companies that have worked on antibiotics;
- Propose innovative sub-projects to be proposed for utilizing any available or recovered data and assets;
- Build and maintain appropriate database of assets;
- Build a team for Antibiotic Memory Recovery Programme.
- Work closely with the project leader exploratory projects, who will also report to the Senior Scientist, in further exploring potential revived antibiotic projects.
- Work closely with the project leaders of the advanced disease projects in fueling the future pipeline.
- Build and manage budget and team for this project.
- Ensure projects coordination (i.e. GANTT charts) for the timely set up and running of these projects and ensure they both deliver information and leads for disease-specific GARDP projects.
Tasks and responsibilities for R&D staff:
- Have an understanding of modern drug discovery and development in the pharmaceutical industry with extensive experience in contributing to and managing complex projects
- Have experience and contacts in the field of antibiotics.
- He/she reports to GARDP Director of Business Development & Corporate Strategy and to GARDP Senior Scientist (once in place).
- He/she has frequent interaction with GARDP staff and external stakeholders to coordinate provision of work or to advocate, persuade and gain support or commitment. He/she represents GARDP for a program/service area and develop and maintain relationship with current and future partners.
Skills and attributes
- High ability to use initiative, prioritize, multi-task, and work well under pressure to meet deadlines.
- Very clear and systematic thinking that demonstrates strong judgment and problem solving competencies.
- Have solid experience in database management tools and possess broad IT competencies.
- Have a proven record in project management and ability to drive the project with many external partners, as well as in the use of project management tools.
- Have excellent (face to face, tele/videoconference, email) communication and presentation skills and be capable of meeting challenging timelines.
- Be reliable, organized, and detail-orientated.
- Have ability to work independently as well as a good team player.
- Have ability to work in a fast-paced environment, sometimes under pressure.
- Have experience working in international environment and with people from different cultural backgrounds.
- Over 10 years’ experience in a senior role.
- Proven ability to work effectively in a team environment and matrix structure.
- Experience of working in public and private sector is highly desirable.
- Advanced post-graduate degree or graduate degree with equivalent in experience to reach Master level.
- Fluency in English.
- Proficiency in local languages desirable.
- Excellent knowledge of Microsoft Suite.
- Status: (Full time – Permanent role).
- Deadline for application: Accepting applications until October 31st.
- Only shortlisted candidates will be contacted.