5th Joint Scientific Meeting HAT Platform – EANETT

3-4 October 2018 
Kampala, Uganda

The theme of the 5th Joint Scientific Meeting HAT Platform-EANETT is “Research and control activities challenges in keeping HAT below the elimination threshold beyond 2020”.

 

Sessions

NTD Elimination: The progress of HAT and new treatment perspectives

Date: Wednesday, 3 October 2018
Time: 9:45-11:20

Chairperson: Abdoulaye Diarra, Regional Office for Africa, World Health Organization
Deputy Chairman: Imna Malele, Vector & Vector-Borne Diseases Research Institute (VVBDI)
Rapporteurs : Barbara Nerima and Anne Nauteza

How to keep HAT below elimination threshold 2020: A situational overview: Keynote Address
José Ramon Franco, Department of Control of Neglected Tropical Diseases, WHO, Switzerland

DNDi’s NTD development programme in Africa
An update on fexinidazole
Nathalie Strub-Wourgaft, NTD Director, DNDi, Switzerland

HAT DNDi programme progress and evolution in the path to elimination
Antoine Tarral, Head of HAT Clinical Programmes, DNDi, Switzerland

 

Epidemiology, operational research & socio-economic issues for HAT elimination – Part 1

Time: 11:20-13:00

Chairperson: Abdoulaye Diarra, Regional Office for Africa, World Health Organization
Deputy Chairman: Imna Malele, Vector & Vector-Borne Diseases Research Institute (VVBDI)
Rapporteurs : Barbara Nerima and Anne Kazibwe

Impact of the Ebola outbreak on sleeping sickness in coastal Guinea: A retrospective analysis (2012-2017) from the Guinean national Human African Trypanosomiasis control program
Oumou Camara, HAT National Control Program, Ministry of Health, Guinea

Geographic distribution of human African trypanosomiasis cases in the Democratic Republic of Congo from 2011 to 2017: Spatial analysis of the HAT Atlas data
Shampa Chancy, HAT National Control Program, Ministry of Health, DRC

Quantifying transmission dynamics of HAT in peri-elimination era through mathematical modelling
Katherine Rock, Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, UK

Risk of resurgence of HAT in low-prevalence conflict areas: case of Kasai Occidental province in the DRC
Samuel Rashidi, HAT National Control Program, Ministry of Health, DRC

Sensing sleeping sickness: local symptom-making in South Sudan
Jennifer Palmer, Medical Anthropologist and Deputy Director, Health in Humanitarian Crises Centre, LSHTM, UK

Innovative tools and quality data to achieve the elimination of sleeping sickness
Alain Mpanya, HAT National Control Program, Ministry of Health, DRC

Human African Trypanosomiasis (HAT), epidemiological, diagnostic, therapeutic and evolutionary aspects in children and adolescents in the three care sites in Guinea
Ansoumane Kourouma, Key Laboratory of Environment and Health, Huazhong University of Science and Technology

An active search strategy for unconfirmed CATT positive suspects set up by a health zone team in the DRC
Matthieu Nkieri, Zone rurale de santé de Bagata

 

Epidemiology, operational research & socio-economic issues for HAT elimination – Part 2

Time: 14:00-15:15

Chairperson: Abdoulaye Diarra, Regional Office for Africa, World Health Organization
Deputy Chairman: Imna Malele, Vector & Vector-Borne Diseases Research Institute (VVBDI)
Rapporteurs : Anne Nauteza and Anne Kazibwe

Enhanced Screening and Diagnosis of gambiense Human African Trypanosomiasis in North-western Uganda – Moving Towards Elimination
Charles Wamboga, National Control Program, Ministry of Health, Uganda

HAT assimilated to witchcraft in endemic areas in the DRC: presentation of a clinical case
Helene Mahenzi, HAT Investigator, DNDi

Enhanced passive screening for HAT in Angola – progress towards elimination
Paulo Makana, Head of Department for Technical Management and Supervision. Institute for Combat and Control of Trypanosomiasis, Angola

Enhanced passive screening for HAT in a troubled transboundary focus in the Republic of Congo
Bienvenu Ossibi, Service des Maladies Infectieuses, CHU-Brazzaville, DRC

Enhanced passive screening for HAT in Kongo Central province of the DRC – progress towards elimination after three years
Simon Kayembe, HAT National Control Program, Ministry of Health, DRC

 

Research for new diagnostic and treatment options – Part 1

Time: 15:15-16:20

Chairperson: Sylvain Bieler, Senior Project Manager, FIND, Switzerland
Deputy Chairman: Augustin Kadima Ebeja, Coordinator, HAT Platform
Rapporteurs : Anne Nauteza and Anne Kazibwe

The immune trypanolysis test as a diagnostic tool for rational follow-up of serological suspects until detection of Trypanosoma brucei gambiense
Jeannette Bahota

Evaluation of the sensitivity of primers used for the PCR diagnosis of human African trypanosomiasis due to Trypanosoma brucei gambiense in guinea costal foci
Hamidou Ilboudou, Researcher at the “Centre International de Recherche-Développement sur l’Elevage en zone Subhumide”, Burkina Faso

Use of the immune trypanolysis test to detect T.b. gambiense-specific antibodies in sera from domestic animals in silent and hypoendemic sleeping sickness foci in the Democratic Republic of the Congo (Foci of Boko-Kivulu and Boma in Kongo Central Province)
Pati Pyana, Quality Specialist, DNDi, DRC

Surveillance model combining rapid testing and collection of filter papers in a network of sentinel sites in North Ecuador, DR Congo
Charles Kambo, CDI Bwamanda, DRC

Performance of diagnostic algorithms based on Rapid Diagnostic Tests to detect sleeping sickness
Jacquies Makabuza, National Sleeping Sickness Control Programme, DRC

 

Research for new diagnostic and treatment options – Part 2

Time: 16:30-18:00

Chairperson: Sylvain Bieler, Senior Project Manager, FIND, Switzerland
Deputy Chairman: Augustin Kadima Ebeja, Coordinator, HAT Platform
Rapporteurs : Anne Nauteza and Anne Kazibwe

Identification of Novel Stage Diagnostic Bio-markers in plasma of Trypanosoma brucei rhodesiense Sleeping Sickness Patients in Uganda
Charles Kato, Department of Bio molecular Resources and Bio laboratory Sciences, Makerere University, Uganda

Increasing the Toolbox for Trypanosomiasis Control: Exploring Efficacy of Metacyclic Antigens for Mammalian Vaccines
Serap Aksoy, Professor of Epidemiology, Department of Epidemiology of Microbial Diseases, Yale University, USA

Potential of Cerebrospinal fluid Interleukin-6 and Neopterin in discriminating between early and late stage Trypanosoma brucei rhodesiense sleeping sickness patients in Uganda
Ansiimwe Immaculate

Therapeutical approach in experimental trypanosomiasis by assessment of posaconazole
Romaric Nzoumbou, Laboratoire de Parasitologie, Université de Bordeaux, France

Evolution of the nutritional status of children included in the DNDiHATFEX006 study in the Democratic Republic of Congo, between the time of diagnosis and the end at 12-month follow-up
Digas Ngolo, Investigator Coordinator, DNDi

Some study on Sulphadimidine, Gentamicin, Oxytetracycline and their Combinations in Nubian Goats Experimentally Infected with Trypanosoma evansi
Fairouz Youssif, Central Veterinary Research Laboratory, Sudan

Description of an active hearth of disease of the sleep in the southern periphery of Kinshasa (DRC), by xénomonitoring
Philemon Mansinsa, National Sleeping Sickness Control Programme, DRC

 

Vector control & genomics/genetics for HAT elimination

Date: Thursday, 4 October 2018
Time
: 8:30-10:30

Chairperson: Grace Murilla
Deputy Chairman: Charles Kato, Department of Bio molecular Resources and Bio laboratory Sciences, Makerere University, Uganda
Rapporteurs : Anne Nauteza and Anne Kazibwe

Improving efficiency and quality in clinical trials in sub-Saharan Africa. Temporal genetic differentiation in Glossina pallidipes tsetse fly populations in Kenya
Winnie Okeyo, Yale School of Public Health, USA, Department of Biomedical Sciences and Technology, Maseno University, and Kenya Agricultural and Livestock Research Organization, Kenya

Spatio-temporal dynamics of African human Trypanosomiasis fly flies in the Nola-Bilolo focus, Central African Republic
Yvon Andjingbopou, University of Bangui, Central African Republic

Molecular Xenomonitoring of Trypanosome in tsetse for prioritizing vector control and HAT elimination in northern Tanzania
Imna Malele, Vector & Vector-Borne Diseases Research Institute (VVBDI)

NGU-2B: An Appropriate Trap for Control and Monitoring of Glossina morsitans morsitans in the Karamoja Drylands Agroecological Zone, Uganda
Patrick Abila, National Livestock Resources Research Institute (NaLIRRI), Uganda

Responses of Glossina pallidipes and

Glossina morsitans morsitans tsetse flies to analogues of δ-octalactone and selected blends
Benson Wachira, Department of Chemistry, Kenyatta University, Kenya

Assessment of the socio-economic and environmental impacts of the project for the creation of tsetse fly and trypanosomosis release zones four years after its closure
Percoma Lassane, The Pan African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC), Burkina Faso

Putative protective association with Human African Trypanosomiasis in Democratic Republic of the Congo by SNPs in IL4 and INFG
Olivier Fataki, Institut National de Recherche Biomedicale, DRC

A spatial genetics approach to inform vector control of tsetse flies (Glossina fuscipes fuscipes) in Northern Uganda
Robert Opiro, Department of Biology, Faculty of Science, Gulu University, Uganda

 

 

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Full programme