PKDL development after combination treatment with miltefosine and paromomycin in a case of visceral leishmaniasis: First ever case report

by Pandey K, Goyal V, Das VNR, Verma N, Rijal S, Das P, and Alvar JJournal of Medical Microbiology and Immunology Research 2018, 2(1).

Summary: This is the first report of the occurrence of post kala azar dermal leishmaniasis (PKDL) after successful treatment of visceral leishmaniasis (VL) with a combination of miltefosine and paromomycin. The case report describes a 10- year-old male patient from Bihar, India who developed maculopapular lesions on the face and trunk one year after successful treatment of VL. PKDL was confirmed by parasitological diagnosis (slit skin smear) of skin lesions for Leishmania donovani. He was treated with amphotericin B deoxycholate injections for PKDL and recovered completely.

Click here to read the article / PDF