Clinical practice guidelines for Chagas disease: Recent developments and future needs

by Forsyth C, Marchiol A, Herazo R, Chatelain E, Batista C, Strub-Wourgaft N, Bilbe G, Sosa-Estani S. Revista da Sociedade Brasileira de Medicina Tropical (Journal of the Brazilian Society of Tropical Medicine) 2019; 52: e20180262. doi:10.1590/0037-8682-0262-2018

Summary: This letter to the editor refers to a review which compared five South American clinical practice guidelines for Chagas disease and concluded that they did not have a strong connection to the best available evidence. The authors agree with the original review that inconsistency in guidelines can create a potential barrier to treatment but note that there is now a greater tendency to use evidence-based guidelines that favour offering treatment to adults with indeterminate chronic infection. While new evidence has strengthened recent clinical practice guidelines, substantial work is required to ensure that evidence-based recommendations are utilized consistently and appropriately in the various countries where Chagas disease is a public health concern.

Click here to read article / PDF