|In the partnership with DNDi on ASAQ development, Sanofi-Aventis (now: Sanofi) contributed resources and expertise in 5 main fields:|
Industrial pharmaceutical development
Development of processes required to reach production on an industrial scale at the Maphar Sanofi-Aventis plant in Casablanca, Morocco.
Pre-clinical pharmaco-toxicology studies were designed to further document the safety profile of AS+AQ in animals, as per the latest international requirements.
Preparation of registration files for Morocco, sub-Saharan malaria endemic countries and WHO pre-qualification process.
Application for the inclusion on the WHO Essential Medicines List.
Preparation of ASAQ launch and marketing in endemic countries, through private and public distribution channels.
Preparation and implementation of follow-up clinical studies.