DNDi aims to deliver:

  • A safe, effective, low-cost and short-course, oral treatment for visceral leishmaniasis.
  • A new treatment for PKDL that is shorter and better tolerated than current options.
  • A new treatment regimen for patients co-infected with HIV and visceral leishmaniasis.
  • A safe, effective, and shorter-course treatment for cutaneous leishmaniasis.

 

The current portfolio for both visceral and cutaneous leishmaniasis includes:

Research

Discovery

Aminopyrazoles
Booster H2L
CGH VL Series 1
Daiichi-Sankyo LH2L
DNDI-5421 & DNDI-5610
Leish H2L
Leish L205 Series
Screening

Translation

Translation

CpG-D35
DNDI-6148
DNDI-0690
DNDI-5561
GSK3186899/DDD853651 – GSK3494245/DDD1305143
New CL Combination Therapies

Development

Development

MF/PM Combination for Africa
New treatments for HIV/VL
New treatments for PKDL
New VL treatments Latin America

Implementation

Implementation

SSG&PM
New VL Treatments – Asia

 

For more details on each project, see DNDi‘s Global Portfolio