Nova terapia com combinação de tratamentos mais acessível economicamente contra a hepatite C, apresenta 97% de taxa de cura

Paris, 12 de abril de 2018
Resultados refoçam uma abordagem de saúde pública para a hepatite C
Uma nova terapia, com combinação de dois diferentes tratamentos, e com custo mais acessível para o tratamento da hepatite C demonstrou segurança e eficácia, com taxas de cura extremamente altas entre os pacientes, incluindo casos difíceis de tratar. O tatameto inclui um novo candidato a fármaco, ravidasvir, e os resultados provisórios são do estudo Fase II/III STORM-C-1, apresentado pela organização de pesquisa e desenvolvimento sem fins lucrativos (Iniciativa Medicamentos para Doenças Negligenciadas (DNDi, pelas siglas em inglês de Drugs for Neglected Diseases initiative) – DNDi) durante a International Liver Conference, que acontece até  dia 15 de abril em Paris.

Nueva combinación para el tratamiento de la hepatitis C con precio accesible muestra una tasa de curación del 97%

Paris, 12 de abril de 2018
Los resultados viabilizan un tratamiento de salud pública para la hepatitis C
Se ha demostrado que un  tratamiento combinado de hepatitis C, a precio más accesible, que incluye el nuevo fármaco candidato ravidasvir, es seguro y eficaz, con tasas de curación extremadamente altas para los pacientes, inclusive en casos difíciles de tratar, según los resultados provisionales del  ensayo de Fase II / III STORM-C-1, expuestos por Drugs for Neglected Diseases IniciativeIniciativa Medicamentos para Enfermedades Olvidadas (DNDi), organización de investigación y desarrollo sin fines de lucro, en la International Liver Conference – Conferencia Internacional del Hígado, en París.

可负担丙型肝炎新联合疗法 治愈率达97%

巴黎,2018年4月12日
试验结果支持从公共卫生角度着手施用丙型肝炎疗程
非营利研发组织DNDi也即是‘被忽视疾病药物研发倡议组织’(Drugs for Neglected Diseases initiative)在巴黎国际肝病大会上发表第II/III期STORM-C-1试验中期结果,显示一种包含新药ravidasvir的丙型肝炎联合疗法不仅安全有效,而且费用可负担得起。此联合疗法可达到极高治愈率,其中包括难治的个案。

Rawatan kombinasi hepatitis C mampu bayar yang baharu menunjukkan 97% kadar kesembuhan

Paris, 12 April 2018
Hasil keputusan menyokong pendekatan kesihatan awam terhadap hepatitis C
Satu rawatan kombinasi hepatitis C mampu bayar yang melibatkan calon ubat terbaharu, ravidasvir telah dibuktikan selamat dan berkesan, dengan kadar kesembuhan yang sangat tinggi kepada pesakit, termasuk kes-kes yang sukar dirawat. Ini ialah hasil keputusan interim ujian percubaan Fasa II/III STORM-C-1 yang dibentangkan oleh pertubuhan penyelidikan dan pembangunan bukan berasaskan keuntungan iaitu inisiatif bagi Ubat untuk Penyakit Yang Diabaikan (DNDi) di Persidangan Hati Antarabangsa di Paris.

Affordable Medicines Now

27-29 June 2018
Washington DC, USA
Rachel Cohen, Regional Executive Director – session on global struggles for affordable medicines

PAGE 2018 Meeting

29 May-1 June 2018
Montreux, Switzerland
DNDi – poster presentation on TB/HIV paediatric co-treatment

Takeda Pharmaceutical and DNDi collaborate to progress a potential new drug for visceral leishmaniasis through the R&D pipeline

Osaka, Japan and Geneva, Switzerland – 5 April 2018
Efforts funded by the Global Health Innovative Technology Fund for pre-clinical and phase I clinical studies
Takeda Pharmaceutical Co., Ltd. and DNDtoday announced that they have signed an agreement to collaborate in conducting preclinical and phase I clinical studies on drug candidate compounds that had been discovered among the aminopyrazole compound class, aimed at developing an innovative drug for the treatment of visceral leishmaniasis (VL).
[Japanese]

MSF Scientific Days 2018

24-25 May 2018
London, UK
Olawale Salami, Paediatric HIV Clinical Project Manager DNDi Africa – poster about the LIVING study on treatment for paediatric HIV

R&D Portfolio Update March 2018: DNDi Sleeping sickness programme

Phase II/III study results confirmed that fexinidazole, DNDi’s first new chemical entity is safe and effective, and presents significant advantages over current treatment as it removes the need for lumbar puncture and systematic patient hospitalization. A regulatory dossier has been submitted to the European Medicines Agency for fexinidazole as the first all-oral treatment for sleeping sickness.