An Improved Treatment Option for Visceral Leishmaniasis available since 2010!

 

Main Advantages of SSG&PM

  • SSG&PM has been shown in clinical trials to be as safe and effective as the current standard treatment of SSG alone for 30 days in East Africa
  • Recommended by the WHO Expert Committee on the Control of Leishmaniases (2010)
  • SSG&PM offers a real cost effective option
    • The total drug cost of the SSG&PM combination is lower than the cost of SSG alone (44 vs 56 USD).
    • SSG&PM has a significantly shorter treatment duration than that of the standard treatment. Intramuscularly once a day for 17 days (versus 30 days).
    • Reduction of treatment duration means cost savings to both health providers and patients.
    • Reduction of treatment duration is also critical to increasing patient turnover during outbreaks.
  • The combination of SSG&PM has the potential to prolong the life of both drugs.
  • Included in the national guidelines of Sudan, South Sudan, Kenya, Uganda, and Ethiopia

 

A Collaborative Partnership

The development of SSG&PM is the result of a collaborative partnership over a period of six years that reflects the benefits of South-South and North-South collaboration in making a new treatment available to patients in need. Partners include

  • DNDi
  • The Leishmaniasis East Africa Platform (LEAP)
  • The National Control Programmes of Kenya, Sudan, Ethiopia, and Uganda
  • Médecins Sans Frontières (MSF)
  • The World Health Organization (WHO)

 

More information:

    
 
Recent Scientific Publications

Clinical Drug Investigation, January 2017
Safety and effectiveness of sodium stibogluconate and paromomycin combination for the treatment of visceral leishmaniasis in eastern Africa: results from a pharmacovigilance programme

 
Patient story

Lemarus Tebawani Lukero is a 23 years old Kenyan who has been suffering from VL for 2 years and is treated with SSG&PM. Read his story.